Genomes hide an overlooked level of biodiversity, genetic structural variation, that is increasingly available thanks to the development of sequencing and bioinformatics. Studying structural variants across populations and species is revealing their relevant role in evolutionary processes such as the formation of species and adaptation to environment. In this seminar, I will provide an overview of the importance of structural genomics variants through a review of literature and detail two cases. (i) Adaptive chromosomal inversions detecting by whole-genome sequencing at shallow coverage in seaweed flies. (ii) Structural variation studied by a combination of short-reads, long-reads and genome graphs in a pair of recently-diverged species whitefish.
Organisé dans le cadre des séminaires Symbiose :
https://www.cesgo.org/symbiose/seminars/the-role-of-structural-genomic-…