Vandenbol, M, P Durand, Bolle, PA, Dion, C, Portetelle, D and Hilger, F (1994), "Sequence analysis of a 40.2 kb DNA fragment located near the left telomere of yeast chromosome X.", Yeast, 10, 12: 1657-62.
Abstract: We have sequenced on both strands a 40,257 bp fragment located near the left
telomere of chromosome X of Saccharomyces cerevisiae. The sequenced
segment contains 21 open reading frames (ORFs) at least 100 amino acids
long. Five of the ORFs correspond to known amino acid sequences: two
hypothetical proteins in the subtelomeric Y' repeat region of 65.4 and
12.8 KDa, the cytochrome B pre-mRNA processing CBP1 protein, the
mitochondrial nuclease NUC1 and the CRT1 protein. Of the 16 remaining
ORFs, eight show highest homologies with the S. cerevisiae hexose
transporters family (two ORFs), the yeast alpha-glucosidase (two
ORFs), the yeast PEP1 precursor, the Escherichia coli galactoside
O-acetyltransferase, the S. cerevisiae 137.7 KDa protein located in the
Y' region and a protein of unknown function of Schizosaccharomyces
pombe. Finally, eight of the ORFs exhibit no significant similarity
with any amino acid sequences described in data banks. DNA sequence
comparison has revealed the presence of different repeated elements
characteristic of yeast chromosome ends. Disruption studies have been
performed on two ORFs encoding putative proteins of unknown function.
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